Rita 21/Rita 28

Rita 21/Rita 28

desogestrel + ethinylestradiol

Manufacturer:

Biolab

Distributor:

Biopharm
Concise Prescribing Info
Contents
Desogestrel 0.15 mg, ethinyl estradiol 0.03 mg, 7 placebo tab (Rita 28 only)
Dosage/Direction for Use
Rita 21 1 tab daily starting on 1st day of menstruation for 21 consecutive days; subsequent courses repeated after 7-day interval. Rita 28 1 tab daily for 21 consecutive days starting on 1st day of menstruation, followed by inert tab for 7 days. Each subsequent pack is started after a 7-day tab-free interval. As w/drawal bleeding occurs w/in 2 or 3 days after the last hormonally active tab, start a new course of 28-day regimen whether bleeding has stopped or not.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Thrombophlebitis, thromboembolic disorders (eg, valvular heart disease w/ thrombogenic complications or atrial fibrillation). History of deep vein thrombophlebitis or pulmonary embolism. Cerebral vascular disease, MI, CAD. Known or suspected breast carcinoma or estrogen-dependent neoplasia; endometrium carcinoma. Hepatic adenomas/carcinoma. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy/jaundice w/ prior pill use. Acute liver disease. Uncontrolled HTN. Headaches w/ focal neurological symptoms. Diabetes w/ vascular complications. Major surgery w/ prolonged immobility. Known or suspected pregnancy.
Special Precautions
Increased risk of serious CV effects & cerebrovascular diseases (especially hypertensive) in women smokers >35 yr; MI in smokers or women w/ other underlying risk factors for CAD eg, HTN, hypercholesterolemia, morbid obesity & diabetes. Discontinue if thromboembolic & thrombotic disorders occurs. Monitor women during treatment & re-examine at least once a yr especially those w/ strong family history of breast cancer or who have breast nodules, fibrocystic disease of the breast, cervical dysplasia or abnormal mammograms. Carefully monitor pre-diabetic & diabetic patients during estrogen-progestin contraceptive therapy. Lactation.
Adverse Reactions
Arterial thromboembolism, cerebral hemorrhage; cerebral thrombosis, coronary thrombosis, focal nodular hyperplasia, gallbladder disease, hepatic adenomas or benign liver tumors, HTN, MI, pulmonary embolism, thrombophlebitis & venous thrombosis w/ or w/o embolism. Dizziness, headache, mental depression, migraine; melasma, rash; breast pain, tenderness, enlargement, secretion; abdominal cramps, nausea, vomiting; amenorrhea during & after treatment, change in cervical erosion & secretion, vag candidiasis; contact lense intolerance; wt change.
Drug Interactions
May decrease contraceptive efficacy & increase breakthrough bleeding w/ rifampin. Decreased contraceptive efficacy w/ other known hepatic microsomal enzyme inducers eg, barbiturates, bosentan, carbamazepine, dexamethasone, griseofulvin, phenytoin, felbamate, oxcarbazepine, rifabutin, modafinil, topiramate, primidone; herbal supplements containing St. John's wort; some HIV-PIs or NNRTIs.
MIMS Class
Oral Contraceptives
ATC Classification
G03AA09 - desogestrel and ethinylestradiol ; Belongs to the class of progestogens and estrogens in fixed combinations. Used as systemic contraceptives.
Presentation/Packing
Form
Rita 21 tab
Packing/Price
1 × 21's
Form
Rita 28 tab
Packing/Price
1 × 28's
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